Dr.-Ing. Christian J. Cyron

Kontakt

 

Berufserfahrung

2015- Technische Universität München, Deutschland
TUM Junior Fellow and Forschungsgruppenleiter
2013 Universidad de Chile, Chile
Gastwissenschaftler, Fakultät für Maschinenwesen
2012-2014   Yale University, USA
Postdoktorand, Fakultät für Medizintechnik
2012 Ecole Polytechnique, Frankreich
Postdoktorand, Institut für Festkörpermechanik
2011 National University of Singapore, Singapore
Gastwissenschaftler, Singapore-MIT Alliance for Research and Technology
2007-2012 Technische Universität München, Deutschland
Wissenschaftlicher Mitarbeiter, Lehrstuhl für Numerische Mechanik
2007 California Institute of Technology, USA
Visiting Student Researcher, Graduate Aeronautical Laboratories

 

Ausbildung

2011-2011   Dr.-Ing., Maschinenwesen, Technische Universität München, Deutschland
2007 Diplom, Maschinenwesen, Technische Universität München, Deutschland

 

Ausgewählte Preise und Auszeichnungen

2015- Aufnahme ins Emmy-Noether-Programm der DFG
2012-2014   Postdoktorandenstipendium des DAAD
2008 E.ON Future Award
2008 Preis der CADFEM GmbH für eine herausragende Diplomarbeit
2007-2009 Stipendium der International Graduate School for Science and Engineering
2007 Stipendium des Fördervereins Kurt Fordan
2006 Rudolf-Diesel-Preis
2006-2007 Stipendium der Studienstiftung des Deutschen Volkes
2004 Bestes Vordiplom in Maschinenwesen an der Technischen Universität München
2002-2007 Stipendium der Begabtenförderung des Freistaats Bayern
2001 Preis der Georg-Dax-Stifung für außergewöhnliche schulische Leistungen
2000 TUMMS-Stipendium der Technischen Universität München
2000-2001 Stipendium der Dr. Geigerschen Stiftung

 

Forschungsinteressen

  • Mehrskalenmodellierung komplexer technischer und biologischer Polymermaterialien
    • Brownsche Dynamik von Polymeren
    • Mikromechanik und statistische Mechanik von Polymermaterialien
    • Konstitutivgesetze für komplexe Polymermaterialien
    • Multiphysik-Modellierung und gekoppelte Probleme
  • Biomechanik und Mechanobiologie
    • Wachstum und Umbau in lebendem Weichgewebe
    • Aneurysmen: Festkörpermechanik, Fluidmechanik, Mechanobiologie
    • Computergestützte Diagnosen in der Medizin
  • Numerische Methoden
    • Finite-Elemente-Methode
    • Netzfreie Maximum-Entropie-Methoden
    • Isogeometrische Analyse
  • Kontinuums- und Strukturmechanik
    • Mechanik dreidimensionaler Balken
    • Variationelle Methoden in der Bruchmechanik
    • Strukturoptimierung

 

Publikationen

Artikel in internationalen Journalen mit Peer-Review

  • Siskind S, Aydin RC, Matta P, Cyron CJ (2017) Higher patient satisfaction with antidepressants correlates with earlier drug release dates across online user-generated medical databases. Pharmacology Research & Perspectives (accepted)
  • Aydin RC, Brandstaeter S, Braeu FA, Steigenberger M, Marcus RP, Nikolaou K, Notohamiprodjo M, Cyron CJ (2017)  Experimental characterization of the biaxial mechanical properties of porcine gastric tissue. Journal of the Mechanical Behavior of Biomedical Materials (DOI: 10.1016/j.jmbbm.2017.07.028)
  • Cyron CJ, Aydin RC (2017) Mechanobiological free energy: a variational approach to tensional homeostasis in tissue equivalents. ZAMM (Journal of Applied Mathematics and Mechanics), 10.1002/zamm.201600126
  • Marcus RP, Koerner E,  Aydin RC, Zinsser D, Finke T, Cyron CJ, Bamberg F, Nikolaou K, Notohamiprodjo M (2017) The Evolution of Radiation Dose over Time: Measurement of a Patient Cohort undergoing Whole-Body Examinations on three Computer Tomography Generations. European Journal of Radiology 86: 63-69
  • Cyron CJ, Humphrey JD (2017) Growth and remodeling of load-bearing biological soft tissues. Meccanica 52: 645
  • Braeu FA, Seitz A, Aydin RC, Cyron CJ (2017) Homogenized constrained mixture models for anisotropic volumetric growth and remodeling. Biomechanics and Modeling in Mechanobiology 16(3), 889-906
  • Cyron CJ, Aydin RC, Humphrey JD (2016) A homogenized constrained mixture (and mechanical analog) model for growth and remodeling of soft tissue. Biomechanics and Modeling in Mechanobiology 15(6): 1389-1403
  • Müller KW, Cyron CJ, Wall WA (2015) Computational analysis of morphologies and phase transitions of crosslinked, semiflexible polymer networks. Proceedings of the Royal Society A 471: 2015033
  • Cyron CJ, Humphrey JD (2015) Preferred fiber orientations in healthy arteries and veins understood from netting analysis. Mathematics and Mechanics of Solids 20: 680-696
  • Ortiz-Bernardin A, Hale JS, Cyron CJ (2015) Volume-averaged nodal projection method for nearly-incompressible elasticity using meshfree and bubble basis functions. Computer methods in applied mechanics and engineering 285: 427-451
  • Cyron CJ, Humphrey JD (2014) Vascular homeostasis and the concept of mechanobiological stability. International Journal of Engineering Science, 85: 203-223
  • Cyron CJ, Wilson JS, Humphrey JD (2014) Mechanobiological stability: a new paradigm to understand the enlargement of aneurysms?. Journal of the Royal Society Interface, 11: 20140680
  • Cyron CJ, Marigo J-J, Sicsic P (2014) Cohesive model approach to the nucleation and propagation of cracks due to a thermal shock. International Journal of Fracture, 174: 51-75
  • Romero I, Urrecha M, Cyron CJ (2014) A torsion-free nonlinear beam model. International Journal of solids and structures, 58: 1–10
  • Cyron CJ, Müller KW, Bausch AR, Wall WA (2013) Micromechanical simulations of biopolymer networks with finite elements. Journal of Computational Physics, 244: 236-251
  • Cyron CJ, Müller KW, Schmoller KM, Bausch AR, Wall WA, Bruinsma RF (2013) Equilibrium phase diagram of semi-flexible polymer networks with linkers. European Physics Letters, 102: 38003
  • Nissen K, Cyron CJ, Gravemeier V, Wall WA (2012) Information-flux method: a meshfree maximum-entropy Petrov-Galerkin method including stabilized finite element methods. Computer methods in applied mechanics and engineering, 241-244: 225-237
  • Bompadre A, Perotti LE, Cyron CJ, Ortiz M (2012) Convergent meshfree approximation schemes of arbitrary order and smoothness. Computer methods in applied mechanics and engineering 221-222: 83-103
  • Cyron CJ, Wall WA (2012) Numerical method for the simulation of the Brownian dynamics of rod-like microstructures with three dimensional nonlinear beam elements. International Journal for Numerical Methods in Engineering 90(8): 955-987
  • Cyron CJ, Wall WA (2010) Consistent finite element approach to Brownian polymer dynamics with anisotropic friction. Physical Review E 82: 066705 (also published online in the Virtual Journal of Biological Physics Research 21(1))
  • Cyron CJ, Nissen K, Gravemeier V, Wall WA (2010) Information flux maximum-entropy approximation schemes for convection-diffusion problems. International Journal for Numerical Methods in Fluids 64: 1180-1200
  • Cyron CJ, Nissen K, Gravemeier V, Wall WA (2010) Stable meshfree methods in fluid mechanics based on Green's functions. Computational Mechanics 46(2): 287-300
  • Cyron CJ, Wall WA (2009) Finite Element approach to Brownian Dynamics of Polymers. Physical Review E 80: 066704 (also published online in the Virtual Journal of Biological Physics Research 18(12))
  • Lieleg O, Schmoller KM, Cyron CJ, Luan Y, Wall WA, Bausch, AR (2009) Structural polymorphism in heterogeneous cytoskeletal networks. Soft Matter 5: 1745-1948
  • Cyron CJ, Arroyo M, Ortiz M (2009) Smooth, second order, non-negative meshfree approximants selected by maximum entropy. International Journal for Numerical Methods in Engineering 79: 1605-1632
  • Wall WA, Frenzel MA, Cyron CJ (2008) Isogeometric structural shape optimization. Computer methods in applied mechanics and engineering 197: 2976-2988

Beiträge in Tagungsbänden und Büchern

  • Cyron CJ, Braeu FA, Seitz A, Aydin RC (2017) A homogenized constrained mixture model for anisotropic volumetric growth and remodeling in intracranial aneurysms, 5th International Conference on Computational and Mathematical Biomedical Engineering, Pittsburgh, USA
  • Bompadre A, Perotti LE, Cyron CJ, Ortiz M (2013) HOLMES: convergent meshfree approximation schemes of arbitrary order and smoothness, Meshfree Methods for Partial Differential Equations VI, Series: Lecture Notes in Computational Science and Engineering, Vol. 89, M. Griebel, M. A. Schweitzer (Eds.), Springer-Verlag Berlin Heidelberg, Deutschland, ISBN 978-3-642-32978-4
  • Müller KW, Cyron CJ, Maier C, Bausch AR, Wall WA (2012) A Computational Approach for the Stochastic Analysis of Biopolymer Networks, European Community on Computational Methods in Applied Sciences Young Investigators Conference, Aveiro, Portugal
  • Wall WA, Cyron CJ, Klöppel T, Meier C, Müller KW (2011) Coupled Problems on the cellular and sub-cellular scale, IV International Conference on Computational Methods for Coupled Problems in Science and Engineering, Kos, Griechenland

Dissertation

Die in den obigen Veröffentlichungen zusammengefassten Forschungsarbeiten wurden in zahlreichen Vorträgen und Postern vorgestellt, die hier aufgelistet sind.

 

Lehre

Vorlesungen, Übungen und Tutorien

  • Tutorium Technische Mechanik III (WS 2003/2004)
  • Tutorium Technische Mechanik III (SS 2004)
  • Tutorium Technische Mechanik III (WS 2004/2005)
  • Praktikum Finite Elemente (WS 2005/2006)
  • Übung Nichtlineare Kontinuumsmechanik (WS 2008/2009)
  • Übung Nichtlineare Kontinuumsmechanik (WS 2009/2010)
  • Übung Nichtlineare Kontinuumsmechanik (WS 2010/2011)
  • Übung Nichtlineare Kontinuumsmechanik (WS 2011/2012)
  • Seminar Engineering Solutions for Biomedical Problems (SS 2015)
  • Vorlesung Wachstum und Anpassung in biologischem Gewebe (SS 2015)
  • Seminar Biomechanics for Clinical Healthcare (SS 2016)
  • Vorlesung Wachstum und Anpassung in biologischem Gewebe (SS 2016)
  • Vorlesung Nichtlineare Kontinuumsmechanik (WS 2016/2017)
  • Seminar Biomechanics for Clinical Healthcare (SS 2017)
  • Vorlesung Biomechanik (SS 2017)
  • Vorlesung Nichtlineare Finite-Elemente-Methoden (SS 2017)
  • Vorlesung Technische Mechanik II (SS 2017)

Betreute Diplom-, Master-, Bachelor- und Semesterarbeiten

  • Maximum-entropy approximation schemes for the numerical solution of steady convection-diffusion-reaction problems 
  • Application of characteristics and Green's functions to numerical stabilization techniques 
  • Isogeometric analysis with 2nd order maximum-entropy approximation schemes 
  • Implementation of a finite element model for the simulation of the diffusion of stiff polymers
  • Validation and Verification of Brownian Polymer Dynamics Simulations with Finite Elements 
  • Implementation of non-linear Reissner beam elements in 2 and 3 dimensions 
  • Comparision between different approaches to the simulation of beams 
  • Implementation of a torsion spring element 
  • Finite-element simulation of viscoelatic polymer networks 
  • Development of a finite element for nonlinear beams based on the formulas of Frenet Serret 
  • Comparison between bead-spring and finite element simulations in polymer physics
  • Implementation of a nonlinear membrane finite element
  • DNA double strand break repair by homologous recombination in Escherichia coli
  • Inverse analysis and uncertainty quantification for vascular growth and remodeling
  • A growth and remodeling formulation for a membrane finite element
  • Added-Mass instabilities in finite element simulations of fluid-structure interactions
  • Experimental determination of the material properties of the stomach
  • Computational modeling of gastric electrophysiology
  • Identification of the mechanical properties of the gastric wall by inverse analysis and biaxial tensile tests
  • Development of an extended gastric electrophysiology model